产品货号：
Z11369
中文名称：
ATG13抗体
英文名称：
Anti-ATG13 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATG13 Antibody |
| 指标别名 | ATG13;Autophagy related protein 13;KIAA0652 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ATG13 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATG13 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ATG13.The immunogen is located within amino acids 450 - 500 of ATG13. |
| 计算分子量 | 57kDa |
| 成分 | ATG13 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATG13 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1.ATG13 forms a complex with ULK1 and ULK2,the mammalian homologs of ATG1,and with FIP200.This complex is a target of TOR phosphorylation under normal conditions;inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13,ULK1 and ULK2,which then leads to autophagy.Knockdown of ATG13 inhibits autophagosome formation. |
| Uniprot ID | O75143 |
| 基因名全称 | ATG13 autophagy related 13 homolog (S.cerevisiae) |
| 蛋白名全称 | ATG13 autophagy related 13 homolog (S.cerevisiae) |
| 推荐稀释比 | ATG13 antibody can be used for detection of ATG13 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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